Maclura pomifera Lectin (MPL/MPA) - HRP (Horseradish Peroxidase)

Maclura pomifera Lectin (MPL/MPA) - HRP (Horseradish Peroxidase)

Price: Regular price $176.00

SKU#: 21510926-1

Product Description

Maclura pomifera agglutinin or lectin (MPA/MPL) is tetrameric plant protein purified by fractionation. MPA has a molecular weight of about 44,000 and consists of four subunits. It has an isoelectric point between pH 4.8 and pH 5.3, and blood group specificity towards A, B, and O (-SA). This lectin has a high affinity for tumor-associated T-antigen disaccharide (Galβ1,3GalNAcα) and many O-linked glycopeptide structures. The structure of Galβ1,3GalNAcα occurs on the surface of tumor cells as a mucin-associated antigenic marker, termed as T-antigen. It is also the central element in O-linked glycopeptide structures on other mammalian glycoproteins.Horseradish peroxidase (HRP) is a 40 kDa protein that catalyzes the oxidation of substrates by hydrogen peroxide, resulting in a colored or fluorescent product or release of light as a byproduct of the reaction. It is most commonly used for blotting, immunoassays and immunohistochemistry methods. Maclura pomifera Lectin (MPL/MPA) is conjugated to HRP at an appropriate ratio to provide optimal staining characteristics.

Technical Specifications

Abbreviation: MPL/MPA
Material Source:: Osage orange
Conjugate:: Horseradish Peroxidase (HRP)
Concentration:: 2 mg/mL
Purity:: High Purity Grade
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: Galβ3GalNAc
Inhibiting or Eluting Sugar:: Galactose
Divalent Ions:: None Required
Mitogenic Activity:: Yes
Lyophilized or Liquid: Liquid
Storage Temperature:: -20°C
Hazardous Shipping:: Non-hazardous

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