Agaricus bisporus Lectin (ABA/ABL) - Pure

Agaricus bisporus Lectin (ABA/ABL) - Pure

Price: Regular price $179.50

SKU#: 21510154-1

Product Description

Affinity-pured Agaricus bisporus agglutinin (ABA) is a tetramer composed of two to four isolectins. ABA has two distinct carbohydrate binding sites, one for galactose-ß-1,3-N-acetylgalactosamine and another for galactose-ß-1,3-N-acetylglucosamine. Agaricus bisporus has an anti-proliferative effect on cancerous cells. ABA can be internalized by clathrin-coated vesicles after binding to surface glycoproteins, thus making ABA an inhibitor of its nuclear import of signal-dependent proteins.

Abbreviation: ABA/ABL
Material Source: Agaricus bisporus Mushroom
Preferred Sugar Specificity: Galactoseβ1-3N-Acetylgalactosamine
Inhibiting or Eluting Sugar: Fetuin
Divalent Ions: None Required
Mitogenic Activity: No
Lyophilized or Liquid: Lyophilized
Storage Temperature: 2-8°C
Hazardous Shipping: Non-hazardous

Technical Specifications

Abbreviation: ABA/ABL
Material Source:: Mushroom
Conjugate:: None
Molecular Weight:: 58.5 kDa
Appearance Form:: Powder
Appearance Color:: White to off-white
Purity:: Affinity purified
Shelf Life:: 2 years
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: Galactoseβ1-3N-Acetylgalactosamine
Inhibiting or Eluting Sugar:: Fetuin
Divalent Ions:: None Required
Mitogenic Activity:: No
Lyophilized or Liquid: Lyophilized
Storage Temperature:: -20°C
Hazardous Shipping:: Non-hazardous


Cancer biomarker, Glycobiology, IHC, Inhibits proliferation of malignant cells without cytotoxicity, Binds sialylated and non-sialylated T antigen


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