Agaricus bisporus Lectin (ABA/ABL) - Pure
Price: Regular price $179.50
Product Description
Affinity-pured Agaricus bisporus agglutinin (ABA) is a tetramer composed of two to four isolectins. ABA has two distinct carbohydrate binding sites, one for galactose-ß-1,3-N-acetylgalactosamine and another for galactose-ß-1,3-N-acetylglucosamine. Agaricus bisporus has an anti-proliferative effect on cancerous cells. ABA can be internalized by clathrin-coated vesicles after binding to surface glycoproteins, thus making ABA an inhibitor of its nuclear import of signal-dependent proteins.
Abbreviation: ABA/ABL
Material Source: Agaricus bisporus Mushroom
Preferred Sugar Specificity: Galactoseβ1-3N-Acetylgalactosamine
Inhibiting or Eluting Sugar: Fetuin
Divalent Ions: None Required
Mitogenic Activity: No
Lyophilized or Liquid: Lyophilized
Storage Temperature: 2-8°C
Hazardous Shipping: Non-hazardous
Technical Specifications
| Abbreviation | : | ABA/ABL |
| Material Source: | : | Mushroom |
| Conjugate: | : | None |
| Molecular Weight: | : | 58.5 kDa |
| Appearance Form: | : | Powder |
| Appearance Color: | : | White to off-white |
| Purity: | : | Affinity purified |
| Shelf Life: | : | 2 years |
| Blood Group Specificity: | : | Non-specific |
| Preferred Sugar Specificity: | : | Galactoseβ1-3N-Acetylgalactosamine |
| Inhibiting or Eluting Sugar: | : | Fetuin |
| Divalent Ions: | : | None Required |
| Mitogenic Activity: | : | No |
| Lyophilized or Liquid | : | Lyophilized |
| Storage Temperature: | : | -20°C |
| Hazardous Shipping: | : | Non-hazardous |
Applications
Cancer biomarker, Glycobiology, IHC, Inhibits proliferation of malignant cells without cytotoxicity, Binds sialylated and non-sialylated T antigen
References
Technical Documentation
Product Information SheetSafety Data Sheet (SDS)
Certificates of Analysis (COA)
