Artocarpus integrifolia Lectin (AIA) - Pure
Price: Regular price $117.00
Product Description
Jacalin lectin (AIA) is purified by affinity chromatography and is tetrameric two-chain structure consisting of four identical protomers with an isoelectric point of pH 7.8. The lectin has specificity for blood group types O (+SA) and T. Jacalin is considered a galactose-specific lectin and elutes with galactose or melibiose. A post-translational proteolytic modification of Jacalin gives the lectin a novel carbohydrate-binding site involving the N terminus of the α-chain. The protein’s structure explains it’s carbohydrate-binding specificity of T-antigen disaccharide Galβ1,3GalNAc. Potent inhibitors of jacalin include D-galactose, β-Met-Gal and 2-deoxy-α-D-galactose.
Technical Specifications
Abbreviation | : | AIA |
Material Source: | : | Jacalin |
Conjugate: | : | None |
Molecular Weight: | : | 66 kDa |
Purity: | : | Affinity purified |
Shelf Life: | : | 2 years |
Blood Group Specificity: | : | O (+SA), T antigen |
Preferred Sugar Specificity: | : | Galβ3GalNAc |
Inhibiting or Eluting Sugar: | : | Galactose or Melibiose |
Divalent Ions: | : | None Required |
Mitogenic Activity: | : | Yes |
Lyophilized or Liquid | : | Lyophilized |
Storage Temperature: | : | -20°C |
Hazardous Shipping: | : | Non-hazardous |