Affinity-pured Agaricus bisporus agglutinin (ABA) (SKU 21510154) is a tetramer composed of two to four isolectins. ABA has two distinct carbohydrate binding sites, one for galactose-ß-1,3-N-acetylgalactosamine and another for galactose-ß-1,3-N-acetylglucosamine. Agaricus bisporus has an anti-proliferative effect on cancerous cells. ABA can be internalized by clathrin-coated vesicles after binding to surface glycoproteins, thus making ABA an inhibitor of its nuclear import of signal-dependent proteins.
Agaricus bisporus Lectin (ABA/ABL) is labeled with fluorescein isothiocyanate (FITC) and has an appropriate number of fluorochromes bound to provide the optimum staining characteristics for this lectin. FITC conjugates have been used in a variety of immunohistochemical and flow cytometry applications.
Material Source: Agaricus bisporus Mushroom
Conjugate: FITC (Fluorescein)
Concentration: 2 mg/mL
Shelf Life: 1 year
Blood Group Specificity: Non-specific
Preferred Sugar Specificity: Galactoseβ1-3N-Acetylgalactosamine
Inhibiting or Eluting Sugar: Fetuin
Divalent Ions: None Required
Excitation: 495 nm
Emission: 515 nm
Mitogenic Activity: No
Lyophilized or Liquid: Liquid
Storage Temperature: 2-8°C
Hazardous Shipping: Non-hazardous