Succinylated Concanavalin A Lectin (Succ Con A) - Texas Red

Product Description

Affinity purified Succinylated concanavalin A (Succ-Con A) is derived from native lectin concanavalin A (Con A). It is a nonagglutinating lectin that has a carbohydrate specificity for α linked mannose and glucose, with a sugar elution of α-methlyglucoside + α-methlymannoside. Succ-Con A have been studied for their effects to induce marked proliferation of human peripheral blood lymphocytes. Succ-Con A exhibits mitogenic action equal to native Con A and both increase lymphocytes levels of cyclic GMP. Unlike Con A, Succ-Con at high concertation does not decrease mitogenic activity. Succ-Con A reversibly prevents the growth of normal cells and restores a normal growth phenotype to transformed cells.

Texas Red is a red-fluorescent dye and when bound to Succinylated Concanavalin A Lectin (Succ Con A) can show the binding pattern of this lectin in cellular imaging applications. There is very little overlap between the emission spectra of Texas Red and FITC making this combination ideal for dual-labeling experiments. Rhodamine dyes, such as Texas Red, are more photostable and less sensitive to pH change when compared to other dyes such as fluorescein.