Sambucus nigra (Elderberry) Lectin (SNA/EBL I) - Mitogen Solution
Price: Regular price $43.28
Product Description
Sambucus nigra Lectin (SNA/EBL I) is an isolectin isolated from elderberry bark and purified by affinity chromatography. SNA I belongs to the group of type 2 ribosome-inactivating proteins and is composed of an A-chain with enzymatic activity and a B-chain with carbohydrate-binding activity. It has specificity for α2,6-linked sialic acid residues, and elutes with the sugar lactose. SNA I can induce apoptosis through the caspase-dependent pathway at low concentrations. This effect depends on the carbohydrate binding of the B-chain and is independent from the catalytic activity of the A-chain.Some lectin trigger mitogenic activities in differentiated or resting cells. These lectins do not cause toxicity. A right concentration of affinity purified Sambucus nigra (Elderberry) Lectin (SNA/EBL I) is provided in a sterile solution for stimulating cells that respond to the lectin.
Technical Specifications
| Appearance Form: | : | Liquid |
| Shelf Life: | : | 1 year |
| Storage Temperature: | : | -20°C |
| Hazardous Shipping: | : | Non-hazardous |
Applications
References
- Inoue K, Wada J, Eguchi J, Nakatsuka A, Teshigawara S, Murakami K, et al. (2013) Urinary Fetuin-A Is a Novel Marker for Diabetic Nephropathy in Type 2 Diabetes Identified by Lectin Microarray. PLoS ONE 8(10): e77118. https://doi.org/10.1371/journal.pone.0077118
