Maclura pomifera Lectin (MPL/MPA) - Cy3

Maclura pomifera Lectin (MPL/MPA) - Cy3
Maclura pomifera (Osage orange) Lectin (MPL/MPA) - Cy3
Product image 1Maclura pomifera Lectin (MPL/MPA) - Cy3
Product image 2Maclura pomifera (Osage orange) Lectin (MPL/MPA) - Cy3

Price: Regular price $153.32

SKU#: 21761122-1

Product Description

Maclura pomifera agglutinin or lectin (MPA/MPL) is tetrameric plant protein purified by fractionation. MPA has a molecular weight of about 44,000 and consists of four subunits. It has an isoelectric point between pH 4.8 and pH 5.3, and blood group specificity towards A, B, and O (-SA). This lectin has a high affinity for tumor-associated T-antigen disaccharide (Galβ1,3GalNAcα) and many O-linked glycopeptide structures. The structure of Galβ1,3GalNAcα occurs on the surface of tumor cells as a mucin-associated antigenic marker, termed as T-antigen. It is also the central element in O-linked glycopeptide structures on other mammalian glycoproteins.

Cy3 can be used to visualize the binding pattern of Maclura pomifera Lectin (MPL/MPA) in cellular imaging and flow cytometry. Cy3 is more photostable than many other fluorophores and can be seen with TRITC filter sets. It is commonly combined with green-fluorescent dyes for dual-labeling.

Technical Specifications

Abbreviation: MPL/MPA
Material Source:: Osage orange
Conjugate:: Cyanine 3 (Cy3)
Concentration:: 1 mg/mL
Molecular Weight:: N/A
Molecular Formula:: N/A
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: Galβ3GalNAc
Inhibiting or Eluting Sugar:: Galactose
Fluorescence:: Orange
Divalent Ions:: None Required
Excitation:: 550 nm
Emission:: 570 nm
Mitogenic Activity:: Yes
Lyophilized or Liquid: Liquid
Storage Temperature:: 2-8°C
Hazardous Shipping:: Non-hazardous

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References

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