Lens culinaris Lectin (LCA/LCH) - Pure
Price: Regular price $247.00
Product Description
Affinity purified Lens culinaris lectin (LCA) is composed of four subunits that consists of an α-chain (MW: 5.7 kDa) and β-chain (MW: 17.5 kDa). It has a carbohydrate specificity toward α-D-mannose and α-D-glucose, eluting with the sugar MeαMan+MeαGlc. This lectin is useful in affinity chromatography columns for the separation of glycoconjugates. The two isomers LCA-A and LCA-B agglutinates human red blood cells, although not blood group specific. Activity of LCA is determined by haemagglutination with human blood and agglutinates a 2% suspension of human erythrocytes at a lectin concentration of 8µg/ml. LCA requires calcium and manganese ions for binding. See other LCA conjugates.
Technical Specifications
Abbreviation | : | LCA/LCH |
Material Source: | : | Lentil |
Conjugate: | : | None |
Molecular Weight: | : | 46 kDa |
Purity: | : | Affinity purified |
Shelf Life: | : | 1 year |
Blood Group Specificity: | : | Non-specific |
Preferred Sugar Specificity: | : | α-Mannose, α-Glucose |
Inhibiting or Eluting Sugar: | : | α-Methylmannoside + α-Methylglucoside |
Divalent Ions: | : | Ca++, Mn++ |
Mitogenic Activity: | : | Yes |
Lyophilized or Liquid | : | Lyophilized |
Storage Temperature: | : | -20°C |
Hazardous Shipping: | : | Non-hazardous |
Applications
Cancer biomarker, Agglutination studies, Separation of glycoconjugates
References
Technical Documentation
Product Information SheetSafety Data Sheet (SDS)
Certificates of Analysis (COA)