Lens culinaris (Lentil) Lectin (LCA/LCH) - Mitogen Solution

Product Description

Affinity purified Lens culinaris lectin (LCA) is composed of four subunits that consists of an α-chain (MW: 5.7 kDa) and β-chain (MW: 17.5 kDa). It has a carbohydrate specificity toward α-D-mannose and α-D-glucose, eluting with the sugar MeαMan+MeαGlc. This lectin is useful in affinity chromatography columns for the separation of glycoconjugates. The two isomers LCA-A and LCA-B agglutinates human red blood cells, although not blood group specific. Activity of LCA is determined by haemagglutination with human blood and agglutinates a 2% suspension of human erythrocytes at a lectin concentration of 8µg/ml. LCA requires calcium and manganese ions for binding. See other LCA conjugates.Some lectin trigger mitogenic activities in differentiated or resting cells. These lectins do not cause toxicity. A right concentration of affinity purified Lens culinaris (Lentil) Lectin (LCA/LCH) is provided in a sterile solution for stimulating cells that respond to the lectin.