Purified by affinity chromatography, Galanthus nivalis lectin (GNL/GNA) is composed of four identical subunits. GNL is a mannose-binding lectin, though [interestingly] it will not bind α-linked glucose. This lectin was one of the original molecules used to understand how proteins recognize carbohydrates. Galanthus nivalis is found to bind to many viral glycoproteins, making it a useful tool in HIV research studies.
Galanthus nivalis Lectin (GNL/GNA) is labeled with tetramethylrhodamine isothiocyanate (TRITC) and has an appropriate number of fluorochromes bound to provide the optimum staining characteristics for this lectin. TRITC is a bright orange or red-fluorescent dye with excitation ideally suited to the 532-nm laser line. TRITC labeled GNL/GNA can be used for cellular imaging applications.