Erythrina cristagalli Lectin (ECL/ECA) - Pure

Erythrina cristagalli Lectin (ECL/ECA) - Pure

Price: Regular price $160.55

SKU#: 21510003-1

Product Description

Erythrina cristagalli lectin or agglutinin (ECL/ECA) is affinity purified lectin consists of two subunits with molecular weights of 28,000 and 26,000. ECL binds to carbohydrate structure in membrane and serum glycoproteins of mammalian cells. The shape of the lectin binding domains may resemble cavity type with Galβ1->4GlcNAc as the core binding site with additional one to four sugar subsites and is most complementary to a linear trisaccharide. Some Galβ1-related oligosaccharides are the major structures for lectin binding. Lectin binding activity can be abolition through sialic acid substitution. This allows for specificity to fractionate and isolate mammalian glycoproteins.

Technical Specifications

Abbreviation: ECL/ECA
Material Source:: Coral tree
Conjugate:: None
Molecular Weight:: 54 kDa
Purity:: Affinity purified
Shelf Life:: 2 years
Blood Group Specificity:: A (-SA)
Preferred Sugar Specificity:: Galβ4GlcNAc
Inhibiting or Eluting Sugar:: Lactose
Divalent Ions:: Ca++, Mn++, Zn++
Mitogenic Activity:: Yes
Lyophilized or Liquid: Lyophilized
Storage Temperature:: -20°C
Hazardous Shipping:: Non-hazardous

Applications

Glycobiology, Isolation of human NK cells

References

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