Artocarpus integrifolia Lectin (AIA) - Texas Red

Artocarpus integrifolia Lectin (AIA) - Texas Red
Artocarpus integrifolia (Jacalin) Lectin (AIA) - Texas Red
Product image 1Artocarpus integrifolia Lectin (AIA) - Texas Red
Product image 2Artocarpus integrifolia (Jacalin) Lectin (AIA) - Texas Red

Price: Regular price $82.40

SKU#: 21761005-1

Product Description

Jacalin lectin (AIA) is purified by affinity chromatography and is tetrameric two-chain structure consisting of four identical protomers with an isoelectric point of pH 7.8. The lectin has specificity for blood group types O (+SA) and T. Jacalin is considered a galactose-specific lectin and elutes with galactose or melibiose. A post-translational proteolytic modification of Jacalin gives the lectin a novel carbohydrate-binding site involving the N terminus of the α-chain. The protein’s structure explains it’s carbohydrate-binding specificity of T-antigen disaccharide Galβ1,3GalNAc. Potent inhibitors of jacalin include D-galactose, β-Met-Gal and 2-deoxy-α-D-galactose.

Texas Red is a red-fluorescent dye and when bound to Artocarpus integrifolia (Jacalin) Lectin (AIA) can show the binding pattern of this lectin in cellular imaging applications. There is very little overlap between the emission spectra of Texas Red and FITC making this combination ideal for dual-labeling experiments. Rhodamine dyes, such as Texas Red, are more photostable and less sensitive to pH change when compared to other dyes such as fluorescein.

Technical Specifications

Abbreviation: AIA
Material Source:: Jacalin
Conjugate:: Texas Red
Concentration:: 5 mg/mL
Purity:: High Purity Grade
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: Galβ3GalNAc
Inhibiting or Eluting Sugar:: Galactose or Melibiose
Fluorescence:: Red
Divalent Ions:: None Required
Excitation:: 595 nm
Emission:: 615 nm
Mitogenic Activity:: Yes
Lyophilized or Liquid: Liquid
Storage Temperature:: 2-8°C
Hazardous Shipping:: Non-hazardous

Applications

References

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