Agaricus bisporus Lectin (ABA/ABL) - AP (Alkaline Phosphatase)
Price: Regular price $159.00
Product Description
Agaricus bisporus agglutinin (ABA) is an affinity-purified tetramer composed of two to four isolectins. ABA has two distinct carbohydrate binding sites, one for galactose-ß-1,3-N-acetylgalactosamine and another for galactose-ß-1,3-N-acetylglucosamine. Agaricus bisporus has an anti-proliferative effect on cancerous cells. ABA can be internalized by clathrin-coated vesicles after binding to surface glycoproteins, thus making ABA an inhibitor of its nuclear import of signal-dependent proteins.
Alkaline phosphatase (AP) is conjugated to affinity purified Agaricus bisporus Lectin (ABA/ABL) to show the binding of ABA/ABL in many applications including Western blotting and ELISA. Alkaline phosphatase is a large protein (140 kDa) that catalyzes the hydrolysis of phosphate groups from a substrate resulting in a colored or fluorescent product. The optimal enzymatic activity of this protein is between pH 8 and 10, and its reaction rate remains linear, improving sensitivity over time.
Technical Specifications
| Abbreviation | : | ABA/ABL |
| Material Source: | : | Mushroom |
| Conjugate: | : | Alkaline Phosphatase (AP) |
| Concentration: | : | 1 mg/mL |
| Purity: | : | High Purity Grade |
| Shelf Life: | : | 1 year |
| Blood Group Specificity: | : | Non-specific |
| Preferred Sugar Specificity: | : | Galactoseβ1-3N-Acetylgalactosamine |
| Inhibiting or Eluting Sugar: | : | Fetuin |
| Divalent Ions: | : | None Required |
| Mitogenic Activity: | : | No |
| Lyophilized or Liquid | : | Liquid |
| Storage Temperature: | : | 2-8°C |
| Hazardous Shipping: | : | Non-hazardous |
