Agaricus bisporus Lectin (ABA/ABL) - Cy3

Agaricus bisporus Lectin (ABA/ABL) - Cy3
Agaricus bisporus (Mushroom) Lectin (ABA/ABL) - Cy3
Product image 1Agaricus bisporus Lectin (ABA/ABL) - Cy3
Product image 2Agaricus bisporus (Mushroom) Lectin (ABA/ABL) - Cy3

Price: Regular price $153.32

SKU#: 21761080-1

Product Description

Agaricus bisporus agglutinin (ABA) is an affinity-purified tetramer composed of two to four isolectins. ABA has two distinct carbohydrate binding sites, one for galactose-ß-1,3-N-acetylgalactosamine and another for galactose-ß-1,3-N-acetylglucosamine. Agaricus bisporus has an anti-proliferative effect on cancerous cells. ABA can be internalized by clathrin-coated vesicles after binding to surface glycoproteins, thus making ABA an inhibitor of its nuclear import of signal-dependent proteins.

Cy3 can be used to viualize the binding pattern of Agaricus bisporus Lectin (ABA/ABL) in cellular imaging and flow cytometry. Cy3 is more photostable than many other flourophores and can be seen with TRITC filter sets. It is commonly combined with green-fluorescent dyes for dual-labeling.

Technical Specifications

Abbreviation: ABA/ABL
Material Source:: Mushroom
Conjugate:: Cyanine 3 (Cy3)
Concentration:: 1 mg/mL
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: Galactoseβ1-3N-Acetylgalactosamine
Inhibiting or Eluting Sugar:: Fetuin
Fluorescence:: Orange
Divalent Ions:: None Required
Excitation:: 550 nm
Emission:: 570 nm
Mitogenic Activity:: No
Lyophilized or Liquid: Liquid
Storage Temperature:: 2-8°C
Hazardous Shipping:: Non-hazardous

Applications

References

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