Galanthus nivalis Lectin (GNL/GNA) - Pure
Price: Regular price $101.22
Product Description
Purified by affinity chromatography, Galanthus nivalis lectin (GNL/GNA) is composed of four identical subunits. Specifically binds to Rat and Mouse IgM but not IgG. GNL is a D-mannose-binding lectin (1,3 or 1,6 -linked), though interestingly, it will not bind α-linked glucose. This lectin was one of the original molecules used to understand how proteins recognize carbohydrates. GNL is not a metalloprotein and does not require ions for binding. Snowdrop Lectin is toxic to insects. Galanthus nivalis is found to bind to many viral glycoproteins. making it a useful tool in HIV research studies.
Recommended Usage: Recommended dilutions of 0.5 – 10 µg / ml in 1XPBS. 15 – 20 µg / ml of GNL lectin will agglutinate rabbit erythrocytes.
Technical Specifications
| Abbreviation | : | GNL/GNA |
| Material Source: | : | Snowdrop |
| Conjugate: | : | None |
| Concentration: | : | 2 mg, 5 mg |
| Molecular Weight: | : | 50 kDa |
| Purity: | : | High Purity Grade |
| Shelf Life: | : | 2 years |
| Blood Group Specificity: | : | Rabbit |
| Preferred Sugar Specificity: | : | αMannose |
| Inhibiting or Eluting Sugar: | : | α-Methylmannoside |
| Divalent Ions: | : | None Required |
| Mitogenic Activity: | : | No |
| Lyophilized or Liquid | : | Lyophilized |
| Storage Temperature: | : | -20°C |
| Hazardous Shipping: | : | Non-hazardous |
Applications
Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Blotting, Bioconjugation, HIV research, Virus isolation, Mouse IgM isolation, Glycobiology
References
- Van Damme EJM. Purification of GNA-Related Lectins from Natural Sources. Methods Mol Biol. 2020;2132:413-419.
