Ulex europaeus Lectin (UEA II) - Separopore® 4B

Ulex europaeus Lectin (UEA II) - Separopore® 4B
Ulex europaeus (Gorse) Lectin (UEA II) - Separopore® 4B
Product image 1Ulex europaeus Lectin (UEA II) - Separopore® 4B
Product image 2Ulex europaeus (Gorse) Lectin (UEA II) - Separopore® 4B

Price: Regular price $125.70

SKU#: 21511204-1

Product Description

Affinity purified Ulex europaeus agglutinin (UEA II) is isolated from gorse seeds and separated from crude extract. This lectin is a glycoprotein that consists of four 24,000 Da monomer subunits that require Ca2+ for binding to its ligands through carbohydrate recognition domain. It is specific for di-N-acetylchitobiose, an oligomer of GlcNAc. The monosaccharide GlcNAc is not an inhibitor of the lectin activity. UEA II has no mitogenic activity and agglutinates type O erythrocytes with greater interest than type A3 erythrocytes. Addition of EDTA eliminates agglutinating activity. Agglutinating activity can be recovered with the addition of calcium.UEA II is a potent inhibitor of the lectin complement pathway following endothelial oxidative stress. The molecular mechanism of UEA II-induced inhibition of the lectin complement pathway appears to be through competition for a common binding site on the endothelial cell and not at the level of mannose-binding lectin (MBL) inhibition. See other UEA II conjugates.Affinity purified Ulex europaeus Lectin (UEA II) is immobilized to Separopore® 4B following CNBr coupling. The final product is stabilized in a buffer to retain maximum activity. The gel can be packed in 1 mL or 5mL.

Technical Specifications

Abbreviation: UEA II
Material Source:: Furze gorse seeds
Conjugate:: Separopore® 4B
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: Fucα1,3Galβ4GlcNAc
Mitogenic Activity:: No
Lyophilized or Liquid: Liquid
Storage Temperature:: 2-8°C
Hazardous Shipping:: Non-hazardous



Close (esc)

10% Discount!

Sign up for our mailing list below and you will receive 10% off your first order of $500.00 or more.

Age verification

By clicking enter you are verifying that you are old enough to consume alcohol.


Shopping Cart

Your cart is currently empty.
Shop now