Ulex europaeus Lectin (UEA I) - Separopore® 4B

Ulex europaeus Lectin (UEA I) - Separopore® 4B
Ulex europaeus (Gorse) Lectin (UEA I) - Separopore® 4B
Product image 1Ulex europaeus Lectin (UEA I) - Separopore® 4B
Product image 2Ulex europaeus (Gorse) Lectin (UEA I) - Separopore® 4B

Price: Regular price $131.45

SKU#: 20120004-1

Product Description

Ulex europaeus agglutinin (UEA I) is affinity purified isolated from gorse seeds and separated from crude extract by affinity chromatography. It is consists of two subunits. The lectin is a glycoprotein that has no mitogenic activity to agglutinates type O erythrocytes, and of a lesser degree to individuals with A2 erythrocytes.UEA I reacts strongly with α(1,2) linked fucose residues but poorly or not at all with α(1,3) or α(1,6)-linked fucose. UEA I is unable to bind internal fucose structures and the presence of an internal α(1,3)-linked fucose on the H type 2 oligosaccharide decreases lectin affinity for this blood group antigen by 3-fold.UEA I has been used as a marker for vascular endothelium and used to identify endothelial cells of benign vascular lesions more specifically than antibodies Factor VII-related antigen. UEA I coated magnetic beads have been used to isolate endothelial cells associated with micro-vessels for subsequent cell culture. This lectin has also been used to differentiate between angiosarcomas and epithelial tumor.Affinity purified UEA I is immobilized to Separapore® 4B following CNBr coupling. The final product is stabilized in a buffer to retain maximum activity. The gel can be packed in 1 mL or 5mL.

Technical Specifications

Abbreviation: UEA I
Material Source:: Furze gorse seeds
Conjugate:: Separopore® 4B
Purity:: High Purity Grade
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: αFucose
Mitogenic Activity:: No
Lyophilized or Liquid: Liquid
Storage Temperature:: 2-8°C
Hazardous Shipping:: Non-hazardous

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