Styphnolobium japonicum Lectin (SJA) - Separopore® 4B

Styphnolobium japonicum Lectin (SJA) - Separopore® 4B
Styphnolobium japonicum (Japanese pagoda tree) Lectin (SJA) - Separoporeëå 4B
Product image 1Styphnolobium japonicum Lectin (SJA) - Separopore® 4B
Product image 2Styphnolobium japonicum (Japanese pagoda tree) Lectin (SJA) - Separoporeëå 4B

Price: Regular price $124.12

SKU#: 21510882-1

Product Description

Styphnolobium japonicum agglutinin (SJA) is affinity purified from Japanese pagoda tree seeds. It consists of two subunits. The subunits can be separated into two subfractions, a D-galactose/N-acetyl-D-galactosamine specific lectin (B-SJA-I) and a D-mannose/D-glucose specific lectin (B-SJA-II). SJA has an isoelectric point between pH 4.9 and pH 5.6 and a carbohydrate specificity towards βGalNAc. This lectin elutes with the sugar GalNAc.

SJA agglutinates all blood group types but has greater affinity for A erythrocytes than of B types, than of O (-SA) types. Binding experiments of the lectin with frozen sections of human kidneys shows specific binding to the endothelia in specimens from blood groups B or AB, thus indicating a D-galactose/N-acetyl-D-galactosamine receptor specificity. SJA lacks mitogenic and immune-suppressive activity.

Affinity purified Styphnolobium japonicum Lectin (SJA) is immobilized to Separopore® 4B following CNBr coupling. The final product is stabilized in a buffer to retain maximum activity. The gel can be packed in 1 mL or 5mL.

Technical Specifications

Abbreviation: SJA
Material Source:: Japanese pagoda tree
Conjugate:: Separopore® 4B
Purity:: High Purity Grade
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: ßGalNAc 
Mitogenic Activity:: No
Lyophilized or Liquid: Liquid
Storage Temperature:: 2-8°C
Hazardous Shipping:: Non-hazardous

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