Styphnolobium japonicum Lectin (SJA) - Pure
Price: Regular price $153.18
Product Description
Styphnolobium japonicum agglutinin (SJA) is affinity purified from Japanese pagoda tree seeds. It consists of two subunits. The subunits can be separated into two subfractions, a D-galactose/N-acetyl-D-galactosamine specific lectin (B-SJA-I) and a D-mannose/D-glucose specific lectin (B-SJA-II). SJA has an isoelectric point between pH 4.9 and pH 5.6 and a carbohydrate specificity towards ?GalNAc. This lectin elutes with the sugar GalNAc.
SJA agglutinates all blood group types but has greater affinity for A erythrocytes than of B types, than of O (-SA) types. Binding experiments of the lectin with frozen sections of human kidneys shows specific binding to the endothelia in specimens from blood groups B or AB, thus indicating a D-galactose/N-acetyl-D-galactosamine receptor specificity. SJA lacks mitogenic and immune-suppressive activity.
Technical Specifications
| Abbreviation | : | SJA |
| Material Source: | : | Japanese pagoda tree |
| Conjugate: | : | None |
| Molecular Weight: | : | 133 kDa |
| Purity: | : | High Purity Grade |
| Shelf Life: | : | 2 years |
| Blood Group Specificity: | : | A>B>O(-SA) |
| Preferred Sugar Specificity: | : | β-N-Acetylgalactosamine |
| Inhibiting or Eluting Sugar: | : | N-Acetylgalactosamine |
| Divalent Ions: | : | Ca++, Mn++ |
| Mitogenic Activity: | : | No |
| Lyophilized or Liquid | : | Lyophilized |
| Storage Temperature: | : | -20°C |
| Hazardous Shipping: | : | Non-hazardous |
