Sambucus nigra Lectin (SNA/EBL I) - FITC (Fluorescein)

Sambucus nigra Lectin (SNA/EBL I) - FITC (Fluorescein)
Sambucus nigra (Elderberry) Lectin (SNA/EBL I) - FITC (Fluorescein)
Product image 1Sambucus nigra Lectin (SNA/EBL I) - FITC (Fluorescein)
Product image 2Sambucus nigra (Elderberry) Lectin (SNA/EBL I) - FITC (Fluorescein)

Price: Regular price $92.83

SKU#: 21761051-1

Product Description

Sambucus nigra Lectin (SNA/EBL I) is an isolectin isolated from elderberry bark and purified by affinity chromatography. SNA I belongs to the group of type 2 ribosome-inactivating proteins and is composed of an A-chain with enzymatic activity and a B-chain with carbohydrate-binding activity. It has specificity for α2,6-linked sialic acid residues, and elutes with the sugar lactose. SNA I can induce apoptosis through the caspase-dependent pathway at low concentrations. This effect depends on the carbohydrate binding of the B-chain and is independent from the catalytic activity of the A-chain.

Sambucus nigra Lectin (SNA/EBL I) is labeled with fluorescein isothiocyanate (FITC) and has an appropriate number of fluorochromes bound to provide the optimum staining characteristics for this lectin. FITC conjugates have been used in a variety of immunohistochemical and flow cytometry applications. 

Technical Specifications

Abbreviation: SNA/EBL I
Material Source:: Elderberry
Conjugate:: FITC (Fluorescein)
Concentration:: 1 mg/mL
Appearance Form:: Liquid
Appearance Color:: Yellow
Purity:: High Purity Grade
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: α2-6 Sialic Acid
Inhibiting or Eluting Sugar:: Lactose > β-Galactose
Fluorescence:: Green
Divalent Ions:: None Required
Excitation:: 495 nm
Emission:: 515 nm
Mitogenic Activity:: Yes
Lyophilized or Liquid: Liquid
Storage Temperature:: 2-8°C
Hazardous Shipping:: Non-hazardous

Applications

References

  • Inoue K, Wada J, Eguchi J, Nakatsuka A, Teshigawara S, Murakami K, et al. (2013) Urinary Fetuin-A Is a Novel Marker for Diabetic Nephropathy in Type 2 Diabetes Identified by Lectin Microarray. PLoS ONE 8(10): e77118. https://doi.org/10.1371/journal.pone.0077118
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