Pisum sativum Lectin (PSA/PSL) - Pure

Pisum sativum Lectin (PSA/PSL) - Pure

Price: Regular price $127.00

SKU#: 21510009-2

Product Description

Affinity purified Pisum sativum lectin or agglutinin (PSA) is a heterodimer that consists of four subunits. It has a carbohydrate specificity towards α-linked mannose-containing oligosaccharides. It’s hemagglutinating activity can be inhibited by glucose, mannose, and sucrose. It does not have a blood group specificity. The N-terminal sequence of the lectin has shown some degree of homology compared to lectins from other legume species. Pisum sativum lectin has also shown mitogenic effect toward murine splenocytes and could inhibit activity of HIV-1 reverse transcriptase. PSA is often used to differentiate virally transformed from normal cells. Calcium and manganese ions are required for activity.

Technical Specifications

Abbreviation: PSA/PSL
Material Source:: Pea
Conjugate:: None
Molecular Weight:: 53 kDa
Purity:: High Purity Grade
Shelf Life:: 2 years
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: α-Mannose, α-Glucose
Inhibiting or Eluting Sugar:: α-Methylmannoside + α-Methylglucoside
Divalent Ions:: Ca++, Mn++
Mitogenic Activity:: Yes
Lyophilized or Liquid: Lyophilized
Storage Temperature:: -20°C
Hazardous Shipping:: Non-hazardous

Applications

Agglutination, Model for carbohydrate recognition of proteins, Separation of lymphoblastic leukemia antigen in kidney cells, Purification of feline T-lymphocytes

References

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