Phaseolus vulgaris Lectin (PHA-E+L) - Macrobeads

Phaseolus vulgaris Lectin (PHA-E+L) - Macrobeads
Phaseolus vulgaris (Kidney bean) Lectin (PHA-E+L) - Macrobeads
Product image 1Phaseolus vulgaris Lectin (PHA-E+L) - Macrobeads
Product image 2Phaseolus vulgaris (Kidney bean) Lectin (PHA-E+L) - Macrobeads

Price: Regular price $88.66

SKU#: 21511133-1

Product Description

Affinity Purified Phaseolus vulgaris lectin (PHA E+L, also known as PHA P, P standing for phytohemagglutinin) is affinity purified lectin consists of two isolectins PHA-E and PHA-L, erythroagglutinin and leucoagglutinin, of which both possess strong mitogenic activity. PHA P has a molecular weight of 126,000 and an isoelectric point between pH 5.2 and pH 6.2. It has a carbohydrate specificity for complex oligosaccharides and elutes with bovine thyroglobulin or acetic acid. This lectin agglutinates blood group A (-SA).

PHA P can be used for mitogenic stimulation to human lymphocytes. It has the potential to induce closer contacts between adjacent cell membranes and has been successfully used for membrane-induced fusion in human oocytes, bovine oocyt, and caprine oocytes. Phytohemagglutinin was direct evidence for the involvement of bacterial lectins in the initiation of infection, the basis for present attempts in academia and industry to apply carbohydrates for anti-adhesion therapy of such diseases.

Separopore® macrobeads are larger size (160-250 micron) than average agarose beads that facilitate coupling of cells and organelles and enzymes. Affinity-purified Phaseolus vulgaris Lectin (PHA-E+L) was immobilized on 4% agarose macrobeads with proper configuration and stability of the lectin.

Technical Specifications

Abbreviation: PHA-E+L
Material Source:: Red kidney bean seeds
Conjugate:: Macrobeads
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: Galß4GlcNAcα2Manα6 (GlcNAcß4) (GlcNAcß4Manα3) Manß4, Galß4GlcNAcß6(GlcNAcß2Manα3) Manα3
Mitogenic Activity:: No
Lyophilized or Liquid: Liquid
Storage Temperature:: 2-8°C
Hazardous Shipping:: Non-hazardous

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