Maclura pomifera Lectin (MPL/MPA) - Separopore® 4B

Maclura pomifera Lectin (MPL/MPA) - Separopore® 4B
Maclura pomifera (Osage orange) Lectin (MPL/MPA) - Separoporeëå 4B
Product image 1Maclura pomifera Lectin (MPL/MPA) - Separopore® 4B
Product image 2Maclura pomifera (Osage orange) Lectin (MPL/MPA) - Separoporeëå 4B

Price: Regular price $134.55

SKU#: 20120065-1

Product Description

Maclura pomifera agglutinin or lectin (MPA/MPL) is tetrameric plant protein purified by fractionation. MPA has a molecular weight of about 44,000 and consists of four subunits. It has an isoelectric point between pH 4.8 and pH 5.3, and blood group specificity towards A, B, and O (-SA). This lectin has a high affinity for tumor-associated T-antigen disaccharide (Galβ1,3GalNAcα) and many O-linked glycopeptide structures. The structure of Galβ1,3GalNAcα occurs on the surface of tumor cells as a mucin-associated antigenic marker, termed as T-antigen. It is also the central element in O-linked glycopeptide structures on other mammalian glycoproteins.

Affinity purified Maclura pomifera Lectin (MPL/MPA) is immobilized to Separopore® 4B following CNBr coupling. The final product is stabilized in a buffer to retain maximum activity. The gel can be packed in 1 mL or 5mL.

Technical Specifications

Abbreviation: MPL/MPA
Material Source:: Osage orange seeds
Conjugate:: Separopore® 4B
Purity:: High Purity Grade
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: Galß3GalNAc
Mitogenic Activity:: No
Lyophilized or Liquid: Liquid
Storage Temperature:: 2-8°C
Hazardous Shipping:: Non-hazardous

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References

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