Griffonia simplicifolia Lectin (GSL I) - MagneZoom™

Griffonia simplicifolia Lectin (GSL I) - MagneZoom™
Griffonia simplicifolia (Bandeiraea) Lectin (GSL I) - MagneZoom_†¢
Product image 1Griffonia simplicifolia Lectin (GSL I) - MagneZoom™
Product image 2Griffonia simplicifolia (Bandeiraea) Lectin (GSL I) - MagneZoom_†¢

Price: Regular price $102.21

SKU#: 21511069-1

Product Description

Griffonia simplicifolia lectin (GSL I) is affinity purified from a woody climbing shrub native to Africa. GSL I is composed of two types of subunits A and B that combine to form tetrameric structures, resulting in five isolectins. This lectin has affinity for terminal α-D-galactosyl residues and terminal N-acetyl-α-D-galactosaminyl residues. The A-rich lectin preferentially agglutinates blood group A erythrocytes and thus appears to be specific for α-N-acetylgalactosamine residues, while the B-rich lectin preferentially agglutinates blood group B cells and is specific for α-galactose residues. This lectin shows specificity for blood group B greater than blood group A1.
GSL I has been reported to bind several glycoproteins including laminin. Since some α-D-galactosyl residues are expressed in endothelial cells of mouse tissues, GSL I can present a highly specific surface of glycosylation pattern in these cells.

Affinity purified Griffonia simplicifolia Lectin (GSL I) is immobilized on aminated paramagnetic beads using EDC and stabilized in a buffer to retain maximum activity. These beads are ideal for iP applications to pull down glycoproteins.

Technical Specifications

Abbreviation: GSL I
Material Source:: Griffonia simplicifolia seeds
Conjugate:: MagneZoom™
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: αGal, αGalNAc
Mitogenic Activity:: No
Lyophilized or Liquid: Liquid
Storage Temperature:: 2-8°C
Hazardous Shipping:: Non-hazardous

Applications

References

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