Datura stramonium Lectin (DSA/DSL) - Separopore® 4B

Datura stramonium Lectin (DSA/DSL) - Separopore® 4B
Datura stramonium (Jimson weed) Lectin (DSA/DSL) - Separoporeëå 4B
Product image 1Datura stramonium Lectin (DSA/DSL) - Separopore® 4B
Product image 2Datura stramonium (Jimson weed) Lectin (DSA/DSL) - Separoporeëå 4B

Price: Regular price $149.00

SKU#: 20120058-1

Product Description

Datura stramonium agglutinin or lectin (DSA/DSL) is purified by affinity chromatography. Seeds of Datura stramonium contain at least three different carbohydrate-binding proteins, and the most prominent lectin is a dimeric glycoprotein composed of two nonidentical subunits that contains 40% carbohydrate. It binds well to N-acetylglucosamine, oligomers, and branched pentasaccharide, including two N-acetylglucosamine disaccharides linked to mannose (β-1,6) and (β-1,2), which is known to be the most potent inhibitor of agglutination. DSL prefers binding to (GlcNAc)2-4 and elutes with the sugar chitin hydrolysate. DSL binds well in the acidic pH range and its affinity decreases above pH 8.0. This agglutinin has blood group A, B, and O specificity. Studies have shown that DSA can act as a biomarker for neoplastic urotherial cells.

Affinity purified Datura stramonium Lectin (DSA/DSL) is immobilized to Separopore® 4B following CNBr coupling. The final product is stabilized in a buffer to retain maximum activity. The gel can be packed in 1 mL or 5mL.

Technical Specifications

Abbreviation: DSA/DSL
Material Source:: Jimson weed seeds
Conjugate:: Separopore® 4B
Purity:: High Purity Grade
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: (GlcNAc) 2-4
Mitogenic Activity:: No
Lyophilized or Liquid: Liquid
Storage Temperature:: 2-8°C
Hazardous Shipping:: Non-hazardous

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