Maclura pomifera Lectin (MPL/MPA) - Semi-Pure
Price: Regular price $362.25
Product Description
Maclura pomifera agglutinin or lectin (MPA/MPL) is tetrameric plant protein purified by fractionation. MPA has a molecular weight of about 44,000 and consists of four subunits. It has an isoelectric point between pH 4.8 and pH 5.3, and blood group specificity towards A, B, and O (-SA). This lectin has a high affinity for tumor-associated T-antigen disaccharide (Galβ1,3GalNAcα) and many O-linked glycopeptide structures. The structure of Galβ1,3GalNAcα occurs on the surface of tumor cells as a mucin-associated antigenic marker, termed as T-antigen. It is also the central element in O-linked glycopeptide structures on other mammalian glycoproteins.
Technical Specifications
| Abbreviation | : | MPL/MPA |
| Material Source: | : | Osage orange |
| Conjugate: | : | None |
| Appearance Form: | : | Powder |
| Preferred Sugar Specificity: | : | Galβ3GalNAc |
| Inhibiting or Eluting Sugar: | : | Galactose |
| Divalent Ions: | : | None Required |
| Mitogenic Activity: | : | Yes |
| Storage Temperature: | : | -20°C |
| Hazardous Shipping: | : | Non-hazardous |
