Succinylated Concanavalin A Lectin (Succ Con A) - Ferritin

Succinylated Concanavalin A Lectin (Succ Con A) - Ferritin
Succinylated Concanavalin A (Jackbean) Lectin (Succ Con A) - Ferritin
Product image 1Succinylated Concanavalin A Lectin (Succ Con A) - Ferritin
Product image 2Succinylated Concanavalin A (Jackbean) Lectin (Succ Con A) - Ferritin

Price: Regular price $207.56

SKU#: 21510986-1

Product Description

Affinity purified Succinylated concanavalin A (Succ-Con A) is derived from native lectin concanavalin A (Con A). It is a nonagglutinating lectin that has a carbohydrate specificity for α linked mannose and glucose, with a sugar elution of α-methlyglucoside + α-methlymannoside. Succ-Con A have been studied for their effects to induce marked proliferation of human peripheral blood lymphocytes. Succ-Con A exhibits mitogenic action equal to native Con A and both increase lymphocytes levels of cyclic GMP. Unlike Con A, Succ-Con at high concertation does not decrease mitogenic activity. Succ-Con A reversibly prevents the growth of normal cells and restores a normal growth phenotype to transformed cells.

Succinylated Concanavalin A Lectin (Succ Con A) is conjugated to ferritin, that has a molecular weight of 474,000 g/mol (all 24 subunits combined). Ferritin-conjugated lectins can be used to visualize localization of specific saccharide moieties and examine the distribution of plasma membrane glycoproteins. These conjugates can be viewed via electron microscopy.

Technical Specifications

Abbreviation: Succ Con A
Material Source:: Jackbean
Conjugate:: Ferritin
Concentration:: 1 mg/mL
Purity:: High Purity Grade
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: α-Mannose, α-Glucose
Inhibiting or Eluting Sugar:: α-Methylmannoside + α-Methylglucoside
Divalent Ions:: Ca++, Mn++
Mitogenic Activity:: Yes
Lyophilized or Liquid: Liquid
Storage Temperature:: -20°C
Hazardous Shipping:: Non-hazardous

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