Sambucus nigra Lectin (SNA/EBL I) is an isolectin isolated from elderberry bark and purified by affinity chromatography. SNA I belongs to the group of type 2 ribosome-inactivating proteins and is composed of an A-chain with enzymatic activity and a B-chain with carbohydrate-binding activity. It has specificity for Î±2,6-linked sialic acid residues, and elutes with the sugar lactose. SNA I can induce apoptosis through the caspase-dependent pathway at low concentrations. This effect depends on the carbohydrate binding of the B-chain and is independent from the catalytic activity of the A-chain.bioWORLD produces crosslinked 6B SeparoporeÂ® appropriately coupled to Sambucus nigra Lectin (SNA/EBL I) to provide a fast flow cartridge which can trap affinity bound material and retain it during washing, followed by elution of affinity purified material. bioWORLDâ€™s SuperTrap cartridges of varies matrices are proven highly effective in protein chromatography.