Psophocarpus tetragonolobus Lectin (PTL/PTA I) - Separopore® 6B SuperTrap™ Cartridge

Product Description

Psophocarpus tetragonolobus lectin (PTL I, psophocarpin B1, a storage protein with chymotrypsin inhibitory activity), is isolated from winged bean seeds and purified by affinity chromatography. The seed contains two lectins in which PTL I is the basic of the two. PTL I is a dimeric glycoprotein with specificity to GalNAc, with eluting sugar GalNAc. This lectin agglutinates trypsinized rabbit and human erythrocytes (type A and B) but not trypsinized human type O erythrocytes. PTL I recognize blood group A-substance derived oligosaccharides such as trisaccharide GalNAcα1-3Galβ1-4Glc. bioWORLD produces crosslinked 6B Separopore® appropriately coupled to Psophocarpus tetragonolobus Lectin (PTL/PTA I) to provide a fast flow cartridge which can trap affinity bound material and retain it during washing, followed by elution of affinity purified material. bioWORLD’s SuperTrap cartridges of varies matrices are proven highly effective in protein chromatography.