Narcissus pseudonarcissus Lectin (NPL/NPA) - Ferritin

Narcissus pseudonarcissus Lectin (NPL/NPA) - Ferritin
Narcissus pseudonarcissus (Lent lily) Lectin (NPL/NPA) - Ferritin
Product image 1Narcissus pseudonarcissus Lectin (NPL/NPA) - Ferritin
Product image 2Narcissus pseudonarcissus (Lent lily) Lectin (NPL/NPA) - Ferritin

Price: Regular price $176.27

SKU#: 21510536-1

Product Description

Narcissus pseudonarcissus lectin or agglutinin (NPL/NPA) is affinity purified composed of four subunits. It agglutinates rabbit erythrocytes but is non-reactive with human erythrocytes. NPA has an isoelectric point between pH 4.2 and pH 4.6 with a specific binding activity toward α-D-mannose, although studies have suggested that the purified lectin may have greater affinity for internal mannosyl residues than for nonreducing terminal units. A buffer washed column elutes the sugar α-methylmannoside.

Human studies have found NPA to be nearly non-mitogenic, but it has been reported through an in vitro study that mitogenicity of NPA is age-related, with lymphoproliferative response of peripheral blood mononuclear cells (PBMC) in umbilical cord blood has a sevenfold increase than adult blood. NPA has also been found to be mitogenic for PBMC from lambs and not adult sheep.

Narcissus pseudonarcissus Lectin (NPL/NPA) is conjugated to ferritin, that has a molecular weight of 474,000 g/mol (all 24 subunits combined). Ferritin-conjugated lectins can be used to visualize localization of specific saccharide moieties and examine the distribution of plasma membrane glycoproteins. These conjugates can be viewed via electron microscopy.

Technical Specifications

Abbreviation: NPL/NPA
Material Source:: Lent lily
Conjugate:: Ferritin
Concentration:: 1 mg/mL
Purity:: High Purity Grade
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: α-Mannose
Inhibiting or Eluting Sugar:: α-Methylmannoside
Divalent Ions:: None Required
Mitogenic Activity:: No
Lyophilized or Liquid: Liquid
Storage Temperature:: -20°C
Hazardous Shipping:: Non-hazardous

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