Momordica charantia Lectin (MCL) - Pure

Momordica charantia Lectin (MCL) - Pure
Momordica charantia (Bitter Gourd) Lectin (MCL) - Pure
Product image 1Momordica charantia Lectin (MCL) - Pure
Product image 2Momordica charantia (Bitter Gourd) Lectin (MCL) - Pure

Price: Regular price $231.62

SKU#: 21511432-1

Product Description

Momordica charantia (MCL) lectin, isolated from seeds, is a D-galactose-specific lectin. It is a tetrameric glycoprotein wtih a molecular weight of 120 kDa. In vivo growth inhibition at different concentrations (6-24 ëµg/mL) of MCL is observed against Ehrlich ascites carcinoma (EAC) cells. After lectin treatment, the level of red blood cell and hemoglobin is increased significantly with the decrease of white blood cells. MCL caused cell cycle arrest at G0/G1 phase of EAC cells. MCL showed toxicity against brine shrimp nauplii with an LC50 value of 49.7 ëµg/mL. Several pathogenic bacteria were agglutinated by MCL in the absence of its inhibitory sugars.
Functionalized forms are available upon inquiry.

Technical Specifications

Abbreviation: MCL
Material Source:: Bitter Gourd
Conjugate:: None
Molecular Weight:: 32 kDa
Appearance Form:: Powder
Appearance Color:: White to off-white
Purity:: Affinity-purified
Shelf Life:: 2 years
Blood Group Specificity:: Rabbit erythrocytes, human erythrocytes
Preferred Sugar Specificity:: Galactose
Inhibiting or Eluting Sugar:: Galactose
Lyophilized or Liquid: Lyophilized
Storage Temperature:: -20ºC
Hazardous Shipping:: Non-hazardous

Applications

References

  • Kabir, S. R., Nabi, M. M., Nurujjaman, M., Reza, M. A., Alam, A. K., Zaman, R. U., ... & Uddin, M. S. (2015). Momordica charantia seed lectin: toxicity, bacterial agglutination and antitumor properties. Applied biochemistry and biotechnology175(5), 2616-2628.
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