Maclura pomifera Lectin (MPL/MPA) - Ferritin

Maclura pomifera Lectin (MPL/MPA) - Ferritin
Maclura pomifera (Osage orange) Lectin (MPL/MPA) - Ferritin
Product image 1Maclura pomifera Lectin (MPL/MPA) - Ferritin
Product image 2Maclura pomifera (Osage orange) Lectin (MPL/MPA) - Ferritin

Price: Regular price $207.56

SKU#: 21510534-1

Product Description

Maclura pomifera agglutinin or lectin (MPA/MPL) is tetrameric plant protein purified by fractionation. MPA has a molecular weight of about 44,000 and consists of four subunits. It has an isoelectric point between pH 4.8 and pH 5.3, and blood group specificity towards A, B, and O (-SA). This lectin has a high affinity for tumor-associated T-antigen disaccharide (Galβ1,3GalNAcα) and many O-linked glycopeptide structures. The structure of Galβ1,3GalNAcα occurs on the surface of tumor cells as a mucin-associated antigenic marker, termed as T-antigen. It is also the central element in O-linked glycopeptide structures on other mammalian glycoproteins.

Maclura pomifera Lectin (MPL/MPA) is conjugated to ferritin, that has a molecular weight of 474,000 g/mol (all 24 subunits combined). Ferritin-conjugated lectins can be used to visualize localization of specific saccharide moieties and examine the distribution of plasma membrane glycoproteins. These conjugates can be viewed via electron microscopy.

Technical Specifications

Abbreviation: MPL/MPA
Material Source:: Osage orange
Conjugate:: Ferritin
Concentration:: 1 mg/mL
Purity:: High Purity Grade
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: Galβ3GalNAc
Inhibiting or Eluting Sugar:: Galactose
Mitogenic Activity:: Yes
Lyophilized or Liquid: Liquid
Storage Temperature:: -20°C
Hazardous Shipping:: Non-hazardous

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References

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