Maclura pomifera Lectin (MPL/MPA) - Colloidal Gold

Maclura pomifera Lectin (MPL/MPA) - Colloidal Gold
Maclura pomifera (Osage orange) Lectin (MPL/MPA) - Colloidal Gold
Product image 1Maclura pomifera Lectin (MPL/MPA) - Colloidal Gold
Product image 2Maclura pomifera (Osage orange) Lectin (MPL/MPA) - Colloidal Gold

Price: Regular price $197.13

SKU#: 21510834-1

Product Description

Maclura pomifera agglutinin or lectin (MPA/MPL) is tetrameric plant protein purified by fractionation. MPA has a molecular weight of about 44,000 and consists of four subunits. It has an isoelectric point between pH 4.8 and pH 5.3, and blood group specificity towards A, B, and O (-SA). This lectin has a high affinity for tumor-associated T-antigen disaccharide (Galβ1,3GalNAcα) and many O-linked glycopeptide structures. The structure of Galβ1,3GalNAcα occurs on the surface of tumor cells as a mucin-associated antigenic marker, termed as T-antigen. It is also the central element in O-linked glycopeptide structures on other mammalian glycoproteins.

Colloidal gold can be used to visualize localization of specific saccharide moieties and examine the distribution of plasma membrane glycoproteins based on the binding pattern of Maclura pomifera Lectin (MPL/MPA). Colloidal gold labeled lectins can be viewed via electron microscopy.

Technical Specifications

Abbreviation: MPL/MPA
Material Source:: Osage orange
Conjugate:: Colloidal Gold
Concentration:: 1 mg/mL
Purity:: High Purity Grade
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: Galβ3GalNAc
Inhibiting or Eluting Sugar:: Galactose
Divalent Ions:: None Required
Excitation:: 550 nm
Emission:: 570 nm
Mitogenic Activity:: Yes
Lyophilized or Liquid: Liquid
Storage Temperature:: 2-8°C
Hazardous Shipping:: Non-hazardous

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References

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