Bauhinia purpurea Lectin (BPL/BPA) - Macrobeads

Bauhinia purpurea Lectin (BPL/BPA) - Macrobeads
Bauhinia purpurea (Camel's foot tree) Lectin (BPL/BPA) - Macrobeads
Product image 1Bauhinia purpurea Lectin (BPL/BPA) - Macrobeads
Product image 2Bauhinia purpurea (Camel's foot tree) Lectin (BPL/BPA) - Macrobeads

Price: Regular price $88.66

SKU#: 21511050-1

Product Description

Bauhinia purpurea agglutinin or lectin (BPA/BPL) is a tetrameric lectin with a molecular weight of 195,000. Binding appears to be highest for glycoconjugates containing galactosyl (β-1,3)N-acetylgalactosamine structures but oligosaccharides with a terminal α-linked N-acetylgalactosamine can also bind. BPA is lactose-specific and elutes with the sugar lactose. It has specificity for blood groups A, B, O (-SA). Treatment of erythrocytes with neuraminidase or trypsin will increase the agglutination reaction, indicating that the receptor is masked by terminal carbohydrates.

Although binding specificity is similar to that of peanut agglutinin, tissue staining patterns of these two lectins are distinct. Makela's group 2 sugars, particularly N-acetyl-D-galactosamine, are potent inhibitors. The native protein appears to be stable in detergent solution.

Separopore® macrobeads are larger size (160-250 micron) than average agarose beads that facilitate coupling of cells and organelles and enzymes. Affinity-purified Bauhinia purpurea Lectin (BPL/BPA) was immobilized on 4% agarose macrobeads with proper configuration and stability of the lectin.

Technical Specifications

Abbreviation: BPL/BPA
Material Source:: Camel's foot tree seeds
Conjugate:: Macrobeads
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: Galß3GalNAc
Mitogenic Activity:: No
Lyophilized or Liquid: Liquid
Storage Temperature:: 2-8°C
Hazardous Shipping:: Non-hazardous

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