Astragalus membranaceus Lectin (AML) - Pure

Astragalus membranaceus Lectin (AML) - Pure
Astragalus membranaceus Lectin (AML) - Pure
Product image 1Astragalus membranaceus Lectin (AML) - Pure
Product image 2Astragalus membranaceus Lectin (AML) - Pure

Price: Regular price $203.90

SKU#: 21511426-1

Product Description

Isolated from the roots of a Chinese herb Astragalus membranaceus (Fisch.) Bunge, AML is a monomeric protein with a molecular mass of 31.5 kDa containing 10.7% neutral sugars. AML is best inhibited by D-galactose and its derivatives with pronounced preference for o-nitrophenyl-ï_-D-galactopyranoside. This lectin is stable in the pH range of 5.0-12.0 and temperatures up to 55C for 30 minutes. AML inhibits the proliferation of HeLa and K562 cell lines, indicating a high potential for antitumor activity.

Functionalized forms are available upon inquiry.

Technical Specifications

Abbreviation: AML
Material Source:: Hung Q
Conjugate:: None
Molecular Weight:: 31.5 kDa
Appearance Form:: Powder
Appearance Color:: White to off-white
Purity:: Affinity-purified
Shelf Life:: 2 years
Blood Group Specificity:: Not determined
Preferred Sugar Specificity:: Galactose
Inhibiting or Eluting Sugar:: Galactose
Divalent Ions:: None Required
Lyophilized or Liquid: Lyophilized
Storage Temperature:: -20ºC
Hazardous Shipping:: Non-hazardous

Applications

References

  • Yan, Q., Zhu, L., Kumar, N., Jiang, Z., & Huang, L. (2010). Characterisation of a novel monomeric lectin (AML) from Astragalus membranaceus with anti-proliferative activity. Food Chemistry122(3), 589-595.
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