Artocarpus integrifolia Lectin (AIA) - Ferritin

Artocarpus integrifolia Lectin (AIA) - Ferritin
Artocarpus integrifolia (Jacalin) Lectin (AIA) - Ferritin
Product image 1Artocarpus integrifolia Lectin (AIA) - Ferritin
Product image 2Artocarpus integrifolia (Jacalin) Lectin (AIA) - Ferritin

Price: Regular price $165.84

SKU#: 21510502-1

Product Description

Jacalin lectin (AIA) is purified by affinity chromatography and is tetrameric two-chain structure consisting of four identical protomers with an isoelectric point of pH 7.8. The lectin has specificity for blood group types O (+SA) and T. Jacalin is considered a galactose-specific lectin and elutes with galactose or melibiose. A post-translational proteolytic modification of Jacalin gives the lectin a novel carbohydrate-binding site involving the N terminus of the α-chain. The protein’s structure explains it’s carbohydrate-binding specificity of T-antigen disaccharide Galβ1,3GalNAc. Potent inhibitors of jacalin include D-galactose, β-Met-Gal and 2-deoxy-α-D-galactose.

Artocarpus integrifolia (Jacalin) Lectin (AIA) is conjugated to ferritin, that has a molecular weight of 474,000 g/mol (all 24 subunits combined). Ferritin-conjugated lectins can be used to visualize localization of specific saccharide moieties and examine the distribution of plasma membrane glycoproteins. These conjugates can be viewed via electron microscopy.

Technical Specifications

Abbreviation: AIA
Material Source:: Jacalin
Conjugate:: Ferritin
Concentration:: 2 mg/mL
Purity:: High Purity Grade
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: Galβ3GalNAc
Inhibiting or Eluting Sugar:: Galactose or Melibiose
Divalent Ions:: None Required
Mitogenic Activity:: Yes
Lyophilized or Liquid: Liquid
Storage Temperature:: 2-8°C
Hazardous Shipping:: Non-hazardous

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