Agaricus bisporus Lectin (ABA/ABL) - Ferritin

Agaricus bisporus Lectin (ABA/ABL) - Ferritin
Agaricus bisporus (Mushroom) Lectin (ABA/ABL) - Ferritin
Product image 1Agaricus bisporus Lectin (ABA/ABL) - Ferritin
Product image 2Agaricus bisporus (Mushroom) Lectin (ABA/ABL) - Ferritin

Price: Regular price $186.70

SKU#: 21510504-1

Product Description

Agaricus bisporus agglutinin (ABA) is an affinity-purified tetramer composed of two to four isolectins. ABA has two distinct carbohydrate binding sites, one for galactose-ß-1,3-N-acetylgalactosamine and another for galactose-ß-1,3-N-acetylglucosamine. Agaricus bisporus has an anti-proliferative effect on cancerous cells. ABA can be internalized by clathrin-coated vesicles after binding to surface glycoproteins, thus making ABA an inhibitor of its nuclear import of signal-dependent proteins.

Agaricus bisporus Lectin (ABA/ABL) is conjugated to ferritin, that has a molecular weight of 474,000 g/mol (all 24 subunits combined). Ferritin-conjugated ABA/ABL can be used to visualize localization of specific saccharide moieties and examine the distribution of plasma membrane glycoproteins. These conjugates can be viewed via electron microscopy.

Technical Specifications

Abbreviation: ABA/ABL
Material Source:: Mushroom
Conjugate:: Ferritin
Concentration:: 1 mg/mL
Purity:: High Purity Grade
Shelf Life:: 1 year
Blood Group Specificity:: Non-specific
Preferred Sugar Specificity:: Galactoseβ1-3N-Acetylgalactosamine
Inhibiting or Eluting Sugar:: Fetuin
Mitogenic Activity:: No
Lyophilized or Liquid: Liquid
Storage Temperature:: 2-8°C
Hazardous Shipping:: Non-hazardous

Applications

References

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