Psophocarpus tetragonolobus Lectin (PTL/PTA II) - Pure
Price: Regular price $158.88
Product Description
Psophocarpus tetragonolobus lectin (PTL II, psophocarpin B1, a storage protein with chymotrypsin inhibitory activity), is isolated from winged bean seeds and purified by fractionation. The seed contains two lectins in which PTL II is the acidic of the two. This lectin agglutinates trypsinized and desialized erythrocytes of all three blood group types (A, B, and O). Nonpolar interactions play an important role in stabilization of the lectin-sugar complex. Projection of ?1,3 linked Gal/GalNAc leads to steric hindrance and prevents the binding of blood group A and B reactive sugars.The unique specificity of PTL II makes it to be useful in isolation and characterization of terminally monofucosylated H-reactive oligosaccharides from those that are difucosylated or internally fucosylated.
Technical Specifications
| Abbreviation | : | PTL/PTA II |
| Material Source: | : | Winged bean |
| Conjugate: | : | None |
| Molecular Weight: | : | 54 kDa |
| Shelf Life: | : | 2 years |
| Blood Group Specificity: | : | O(-SA) |
| Preferred Sugar Specificity: | : | N-Acetylgalactosamine, Galactose |
| Inhibiting or Eluting Sugar: | : | N-Acetylgalactosamine |
| Divalent Ions: | : | Ca++, Mn++ |
| Mitogenic Activity: | : | No |
| Lyophilized or Liquid | : | Lyophilized |
| Storage Temperature: | : | -20°C |
| Hazardous Shipping: | : | Non-hazardous |
Applications
Glycobiology, Blood vessel staining for O blood groups
References
Technical Documentation
Product Information SheetSafety Data Sheet (SDS)
Certificates of Analysis (COA)
